bromelain

Literature Review

Bromelain-Based Enzymatic Debridement: Mechanism of Action in the Wound Environment. A Literature Review

01/02/2025

This review focuses on the mechanism of action and clinical function of bromelain-based enzymatic debridement (BBD) in the context of wound care, focusing on the mechanism of action of BBD and its formulation for chronic wounds in particular.

This review focuses on the...

01/02/2025

Wounds

Literature Review

Proteolytic Enzymes and Wound Debridement: A Literature Review

11/13/2024

Evdoxia Mathioudaki , PharmD, MSc;

Andreas Vitsos , PharmD, MSc, PhD;

Michail Christou Rallis , PharmD, MSc, PhD;

Objective: To summarize the existing literature on the role of proteolytic enzymes in wound debridement, with a focus on their applications, benefits, limitations, and future potential in wound care management.

Objective: To summarize the...

11/13/2024

Wounds

Original Research

An Open-Label, Proof-of-Concept Study Assessing the Effects of Bromelain-Based Enzymatic Debridement on Biofilm and Microbial Loads in Patients With Venous Leg Ulcers and Diabetic Foot Ulcers

12/20/2023

Robert J. Snyder , MD, PhD, DPM, FACFAS, CWS-P, MBA;

Adam J. Singer ;

Cyaandi R. Dove , DPM;

Yaron Shoham ;

Edward Grant ;

Garth A. James ;

Aya Ben Yaakov ;

Stephen Heisler ;

Elinor deLancey Pulcini ;

Lior Rosenberg ;

Howard Petusevsky ;

This study examines the efficacy of a bromelain-based debridement agent for reduction of biofilm in patients with chronic wounds, including diabetic foot ulcers and venous leg ulcers.

This study examines the efficacy...

12/20/2023

Wounds