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Introduction: Decellularized extracellular matrix (ECM) medical devices can facilitate healing of hard-to-heal wounds by acting as a scaffold. A novel decellularized porcine placental ECM...
11/01/2024

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Introduction: Colonization of pathogens in wounds significantly inhibits wound healing and is a major factor in the failure of wounds treated with skin grafts and skin substitutes.  Synth...
11/01/2024
Introduction: It has been researched and well documented that placental tissue has a plethora of growth factors present. Many of these factors are beneficial when it comes to wound treatm...
11/01/2024
Introduction: Povidone polymer stabilizes and improves the use of iodine to reduce wound infections, but iodine is a weak oxidizer and not biocompatible.  A halohydantoin-based polymer ex...
11/01/2024

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Introduction: Amniotic membrane is a promising biomaterial for regenerative medicine, with numerous placental membrane products available on the market for various applications.  A standa...
11/01/2024
Introduction: Biofilms are a common problem in chronic wounds. A thermo-reversible antimicrobial hydrogel (TRH) containing polyhexanide (PHMB) has previously been shown to be effective ag...
11/01/2024
Introduction: The immune system is central to progressing an injury through the wound healing cascade. However, comorbidities often lead to dysregulation of the inflammatory response and ...
11/01/2024

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Introduction: The interplay between fibroblasts and extracellular matrix (ECM) proteins is an important factor in the normal wound healing cascade. Matrix metalloproteinases (MMPs) are ce...
11/01/2024
Introduction: Placenta-based scaffolds are known for their regenerative potential in various clinical applications, often requiring terminal sterilization to ensure safety. The choice of ...
11/01/2024
Introduction: Collagen-based wound matrices are widely used for treating acute and chronic wounds due to their role in wound management. The addition of an antimicrobial to these matrices...
11/01/2024

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