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Objective: Assessment of incremental clinical and economic burdens of relapse in patients with major depressive disorder (MDD).
11/22/2019
Introduction: Lumateperone (lumateperone tosylate, ITI-007) is in late-phase clinical development for schizophrenia. Lumateperone has a unique mechanism of action that simultaneously modu...
11/22/2019
Background: Studies examining treatment responses to antidepressants based on genotype have produced inconsistent findings. Although catechol-O-methyltransferase (COMT) metabolizes catech...
11/22/2019
Background: Tracking medication adherence through an ingestible event monitoring (IEM) sensor could benefit seriously mentally ill patients (SMI). Psychiatric providers may be reluctant t...
11/22/2019
Background: Schizophrenia is a chronic mental disorder that affects ~0.3-0.7% of the population worldwide and poses a significant economic and societal burden. Objectives: To describe tr...
11/22/2019
Background: Medication adherence is critical for relapse prevention among SMI patients. In the absence of objectively collected adherence data (OCAD), managing medications is difficult. A...
11/22/2019
BACKGROUND: In the 12-week ARM-TD and AIM-TD studies of patients with tardive dyskinesia (TD), the percentage of patients achieving ≥50% and ≥70% responses (i.e. reductions from baseline ...
11/22/2019
Background: Post-hoc analyses of the QUALIFY study (1), comparing effects of aripiprazole once-monthly (AOM 400) and paliperidone palmitate once-monthly (PP1M) treatment in patients with ...
11/22/2019
Background: SEP-363856 is a novel trace amine associated receptor-1 (TAAR1)/5-HT1A agonist with no dopamine-D2/5-HT2A antagonist activity which has shown efficacy in animal models of psyc...
11/22/2019
Objective: To assess health-related quality of life (HRQoL) and health status of patients with treatment resistant depression (TRD), treated with esketamine nasal spray+oral antidepressan...
11/22/2019

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