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The Current Treatment Landscape for NSCLC
At the 23rd Annual Perspectives in Thoracic Oncology meeting, Abigail Berman, MD, MSCE, Assistant Professor, Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, spoke about the current treatment landscape for patients with NSCLC, and how it has evolved in the past few years.
Transcript
Patients are now receiving for locally advanced non-small cell lung cancer chemoradiation followed by immunotherapy. This brings up several toxicity concerns. First of all, immunotherapy has a risk of pneumonitis, as does radiation. Whether or not each has its individual risk or whether those risks are in fact additive is unknown.
We're concerned about the risk of pneumonitis. In addition, there are other risks that go along with immunotherapy that may be additive with chemoradiation, whether it's given sequentially as it was done in the PACIFIC trial, or whether or not there's a role for moving immunotherapy into the concurrent setting.
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