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Opioid Use Associated With Fractures in People With Ankylosing Spondylitis
12/20/2023
Increasing age, historical fracture, and opioid use are associated with higher odds of fracture in ankylosing spondylitis (AS), according to a study published in Arthritis Care & Research. “We performed a retrospective cohort study...
Increasing age, historical fracture, and opioid use are associated with higher odds of fracture in ankylosing spondylitis (AS), according to a study published in Arthritis Care & Research. “We performed a retrospective cohort study...
Increasing age, historical...
12/20/2023
First Report Managed Care
News
Managing Treatment Burden in PsA and RA: Patients' Views on Methotrexate and TNFi Use
12/15/2023
“Patients experience a wide range of burden associated with treatments used for PsA and RA,” said researchers.
“Patients experience a wide range of burden associated with treatments used for PsA and RA,” said researchers.
“Patients experience a wide...
12/15/2023
First Report Managed Care
News

Delphi Methodology Establishes Consensus About Demodex Blepharitis Signs, Symptoms, and Diagnosis
12/15/2023
The Delphi methodology effectively establishes consensus on the diagnosis of Demodex blepharitis (DB), including signs and symptoms, but does not determine the best course of treatment or how to grade the severity of the disease, according to...
The Delphi methodology effectively establishes consensus on the diagnosis of Demodex blepharitis (DB), including signs and symptoms, but does not determine the best course of treatment or how to grade the severity of the disease, according to...
The Delphi methodology...
12/15/2023
First Report Managed Care
News
Hot Topics From the 2023 PCMA Annual Meeting
12/14/2023
The 2023 PCMA annual meeting had a wide variety of topics across the PBM and specialty pharmacy spectrum.
The 2023 PCMA annual meeting had a wide variety of topics across the PBM and specialty pharmacy spectrum.
The 2023 PCMA annual meeting had...
12/14/2023
First Report Managed Care
News
Cautious Excitement Follows First-in-Human Stem Cell Trial for Progressive MS
12/14/2023
Fifteen patients with secondary progressive multiple sclerosis (MS) showed stability in lesion load, brain activity, and clinical and laboratory outcomes, with no serious adverse events, 12 months after receiving an injection of human stem...
Fifteen patients with secondary progressive multiple sclerosis (MS) showed stability in lesion load, brain activity, and clinical and laboratory outcomes, with no serious adverse events, 12 months after receiving an injection of human stem...
Fifteen patients with secondary...
12/14/2023
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News
Antibody Test Determines Eligibility for Hemophilia Gene Therapy
12/11/2023
The US Food and Drug Administration’s recent approval of the AAV5 DetectCDx test marked the agency’s first-ever approval of a companion diagnostic test for a gene therapy product.
The US Food and Drug Administration’s recent approval of the AAV5 DetectCDx test marked the agency’s first-ever approval of a companion diagnostic test for a gene therapy product.
The US Food and Drug...
12/11/2023
First Report Managed Care
News
Skinny-Label Biosimilars Saved Medicare $1.5 Billion Through 2020
12/11/2023
Between 2015 and 2021, 33 biosimilars of 11 biologic drugs received FDA approval. Two-thirds of the biosimilars had skinny labels, according to the study. Among 21 biosimilars marketed before 2022, 13 had skinny labels.
Between 2015 and 2021, 33 biosimilars of 11 biologic drugs received FDA approval. Two-thirds of the biosimilars had skinny labels, according to the study. Among 21 biosimilars marketed before 2022, 13 had skinny labels.
Between 2015 and 2021, 33...
12/11/2023
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News
Gender, Race, Health, and Limitation Status May Help Target Interventions to Increase Physical Activity Among Patients With Asthma
12/08/2023
Targeted interventions to increase physical activity among US adults with asthma may benefit from considering gender, race, health status, and limitation status, according to a study published in the Journal of Asthma.
Targeted interventions to increase physical activity among US adults with asthma may benefit from considering gender, race, health status, and limitation status, according to a study published in the Journal of Asthma.
Targeted interventions to...
12/08/2023
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News
High-Efficacy Therapies for Treatment-Naïve Patients With Relapsing–Remitting MS
12/05/2023
“By minimizing the accumulation of neurological damage early in the disease course, early treatment with HETs may enhance long-term clinical outcomes over the lifetime of the patient,” said researchers.
“By minimizing the accumulation of neurological damage early in the disease course, early treatment with HETs may enhance long-term clinical outcomes over the lifetime of the patient,” said researchers.
“By minimizing the accumulation...
12/05/2023
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News
Research Indicates Biosimilar-to-Biosimilar Switching in Chronic Inflammatory Diseases Safe
12/04/2023
Research indicates that switching between biosimilars is safe and effective, supporting the use of biosimilars to decrease costs and improve access to biological medicines.
Research indicates that switching between biosimilars is safe and effective, supporting the use of biosimilars to decrease costs and improve access to biological medicines.
Research indicates that...
12/04/2023
First Report Managed Care

Behind the Bill

Behind the Bill
The Nondelegation Doctrine: The Next Constitutional Showdown (Part 1)
02/12/2025
Just when you thought the dust had settled from the Chevron decision, the Supreme Court is gearing up to hear arguments in Federal Communications Commission v Consumers' Research next month, potentially reviving the long-dormant nondelegation...
Just when you thought the dust had settled from the Chevron decision, the Supreme Court is gearing up to hear arguments in Federal Communications Commission v Consumers' Research next month, potentially reviving the long-dormant nondelegation...
Just when you thought the dust...
02/12/2025
First Report Managed Care
Behind the Bill
No, President Trump Did Not Actually Sign an Executive Order That Would Increase Drug Costs for Beneficiaries
02/05/2025
On inauguration day, President Trump issued an executive order rescinding several Biden-era health care initiatives, including 3 experimental drug pricing models developed by the Center for Medicare and Medicaid Innovation (CMMI). Oh boy did...
On inauguration day, President Trump issued an executive order rescinding several Biden-era health care initiatives, including 3 experimental drug pricing models developed by the Center for Medicare and Medicaid Innovation (CMMI). Oh boy did...
On inauguration day, President...
02/05/2025
First Report Managed Care
Behind the Bill
Robert F. Kennedy Jr’s Confirmation and the Unexpected Turn in the Drug Pricing Debate
01/29/2025
The Plot Thickens in Drug Pricing Drama Just when you thought the drug pricing debate couldn't get more interesting, Robert F. Kennedy Jr adds an unexpected twist. During closed-door Senate meetings, President Trump’s US Department of...
The Plot Thickens in Drug Pricing Drama Just when you thought the drug pricing debate couldn't get more interesting, Robert F. Kennedy Jr adds an unexpected twist. During closed-door Senate meetings, President Trump’s US Department of...
The Plot Thickens in Drug...
01/29/2025
First Report Managed Care
Behind the Bill
Medicare Drug Negotiations 2.0: New Administration, Same Mission?
01/22/2025
Last week brought 2 major developments in health care policy: President Trump's inauguration and the Centers for Medicare and Medicaid Services’ (CMS) announcement of 15 additional drugs selected for Medicare price negotiations. While these...
Last week brought 2 major developments in health care policy: President Trump's inauguration and the Centers for Medicare and Medicaid Services’ (CMS) announcement of 15 additional drugs selected for Medicare price negotiations. While these...
Last week brought 2 major...
01/22/2025
First Report Managed Care
Behind the Bill
The First 100 Days: Health Care's Critical Deadlines in 2025
01/15/2025
The 119th Congress faces immediate health care deadlines amid significant leadership transitions. While much attention focuses on high-profile nominations like Dr Oz for Centers for Medicare and Medicaid Services (CMS) Administrator and...
The 119th Congress faces immediate health care deadlines amid significant leadership transitions. While much attention focuses on high-profile nominations like Dr Oz for Centers for Medicare and Medicaid Services (CMS) Administrator and...
The 119th Congress faces...
01/15/2025
First Report Managed Care
Behind the Bill
Trump's Executive Orders in a Post-Chevron World: Implications for Health Care Policy
01/08/2025
Happy New Year! As we dive into 2025, it’s clear that this year promises to bring significant changes to health care. With President-elect Donald Trump's inauguration just weeks away, the spotlight is already shifting to how his...
Happy New Year! As we dive into 2025, it’s clear that this year promises to bring significant changes to health care. With President-elect Donald Trump's inauguration just weeks away, the spotlight is already shifting to how his...
Happy New Year! As we dive into...
01/08/2025
First Report Managed Care
Behind the Bill
A Tale of Two Congresses—Health Care Policy in the 117th vs 118th
12/18/2024
The 118th Congress is wrapping up with a whimper rather than a bang when it comes to health care legislation, particularly compared to its predecessor's transformative impact on pharmaceutical policy. As we reflect on these past 4 years, the...
The 118th Congress is wrapping up with a whimper rather than a bang when it comes to health care legislation, particularly compared to its predecessor's transformative impact on pharmaceutical policy. As we reflect on these past 4 years, the...
The 118th Congress is wrapping...
12/18/2024
First Report Managed Care
Behind the Bill
Medicare Privatization Under New CMS Leadership: What's Really at Stake
12/11/2024
After writing about Dr Oz's potential impact on Medicare drug negotiations last week, I found myself diving deeper into an aspect of his nomination that deserves closer attention: his vision for Medicare's future. A letter from Senate...
After writing about Dr Oz's potential impact on Medicare drug negotiations last week, I found myself diving deeper into an aspect of his nomination that deserves closer attention: his vision for Medicare's future. A letter from Senate...
After writing about Dr Oz's...
12/11/2024
First Report Managed Care
Behind the Bill
Medicare Drug Negotiations Under New CMS Leadership
12/04/2024
President-elect Donald Trump nominated Dr Mehmet Oz to lead the Centers for Medicare & Medicaid Services (CMS). With this potential change in leadership, are there any implications for Medicare’s drug price negotiation program,...
President-elect Donald Trump nominated Dr Mehmet Oz to lead the Centers for Medicare & Medicaid Services (CMS). With this potential change in leadership, are there any implications for Medicare’s drug price negotiation program,...
President-elect Donald Trump...
12/04/2024
First Report Managed Care
Behind the Bill

When Recess Isn’t a Break: What NLRB v Canning Means for HHS
11/20/2024
As Robert F. Kennedy Jr’s nomination for Secretary of Health and Human Services (HHS) moves through the Senate, there’s growing discussion about whether a recess appointment could be used to bypass confirmation challenges. The Supreme Court’s...
As Robert F. Kennedy Jr’s nomination for Secretary of Health and Human Services (HHS) moves through the Senate, there’s growing discussion about whether a recess appointment could be used to bypass confirmation challenges. The Supreme Court’s...
As Robert F. Kennedy Jr’s...
11/20/2024
First Report Managed Care

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