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February 2013 - FRMC

02/14/2013
Despite an extensive and widely available childhood vaccination program, pertussis remains a poorly controlled vaccine-preventable disease in the United States. Infants have higher rates of pertussis compared with children in other age...
Despite an extensive and widely available childhood vaccination program, pertussis remains a poorly controlled vaccine-preventable disease in the United States. Infants have higher rates of pertussis compared with children in other age...
Despite an extensive and widely...
02/14/2013
First Report Managed Care
02/14/2013
The treatment of metastatic melanoma has been greatly enhanced by pharmacologic inhibition of the mitogen-activated protein kinase (MAPK) pathway. Trametinib mediates blockade of MAPK kinase (MEK), which is downstream of BRAF in the MAPK...
The treatment of metastatic melanoma has been greatly enhanced by pharmacologic inhibition of the mitogen-activated protein kinase (MAPK) pathway. Trametinib mediates blockade of MAPK kinase (MEK), which is downstream of BRAF in the MAPK...
The treatment of metastatic...
02/14/2013
First Report Managed Care
02/14/2013
Berlin, Germany—After controlling for several variables, patients with Parkinson’s disease who began therapy with rasagiline had a significantly lower probability of being hospitalized, significantly fewer hospitalizations, and shorter length...
Berlin, Germany—After controlling for several variables, patients with Parkinson’s disease who began therapy with rasagiline had a significantly lower probability of being hospitalized, significantly fewer hospitalizations, and shorter length...
Berlin, Germany—After...
02/14/2013
First Report Managed Care
02/14/2013
Berlin, Germany—A database analysis of insured women found that those who took 84 days of levonorgestrel/ethinyl estradiol plus ethinyl estradiol 0.01 mg for 7 days were significantly less likely to become pregnant compared with those who...
Berlin, Germany—A database analysis of insured women found that those who took 84 days of levonorgestrel/ethinyl estradiol plus ethinyl estradiol 0.01 mg for 7 days were significantly less likely to become pregnant compared with those who...
Berlin, Germany—A database...
02/14/2013
First Report Managed Care
02/14/2013
Atlanta—A retrospective cohort analysis found that total healthcare costs for Medicare patients with myeloproliferative neoplasms (MPNs) were 1.5 to 3 times higher and hospitalizations were significantly higher compared with a matched control...
Atlanta—A retrospective cohort analysis found that total healthcare costs for Medicare patients with myeloproliferative neoplasms (MPNs) were 1.5 to 3 times higher and hospitalizations were significantly higher compared with a matched control...
Atlanta—A retrospective cohort...
02/14/2013
First Report Managed Care
02/14/2013
Atlanta—A phase 2, open-label trial found that a subset of patients with double refractory, treatment-resistant acute myeloid leukemia (AML) achieved a clinically meaningful high response rate when taking quizartinib, an oral investigational...
Atlanta—A phase 2, open-label trial found that a subset of patients with double refractory, treatment-resistant acute myeloid leukemia (AML) achieved a clinically meaningful high response rate when taking quizartinib, an oral investigational...
Atlanta—A phase 2, open-label...
02/14/2013
First Report Managed Care
02/14/2013
Atlanta—Patients who took 2.5 mg or 5 mg of apixaban twice daily for 1 year had an 80% risk reduction in recurrent nonfatal or fatal venous thromboembolism (VTE) compared with those who received placebo, according to a randomized,...
Atlanta—Patients who took 2.5 mg or 5 mg of apixaban twice daily for 1 year had an 80% risk reduction in recurrent nonfatal or fatal venous thromboembolism (VTE) compared with those who received placebo, according to a randomized,...
Atlanta—Patients who took 2.5 mg...
02/14/2013
First Report Managed Care
02/14/2013
Atlanta—Patients with previously untreated multiple myeloma, who took the investigational agent MLN9708 in combination with lenalidomide and dexamethasone, responded well to the drug regimen and tolerated the treatment, according to a phase...
Atlanta—Patients with previously untreated multiple myeloma, who took the investigational agent MLN9708 in combination with lenalidomide and dexamethasone, responded well to the drug regimen and tolerated the treatment, according to a phase...
Atlanta—Patients with previously...
02/14/2013
First Report Managed Care
02/14/2013
Atlanta—After a median >12 months of treatment, patients with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who took ponatinib responded well to the drug, according to a phase 2,...
Atlanta—After a median >12 months of treatment, patients with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who took ponatinib responded well to the drug, according to a phase 2,...
Atlanta—After a median >12...
02/14/2013
First Report Managed Care

Department

Conference Insider
02/14/2013
Atlanta—Patients undergoing total hip or knee replacement who took 220 mg of dabigatran etexilate daily had few major bleeding events regardless of their body mass index (BMI), renal function, or age, according to an international,...
Atlanta—Patients undergoing total hip or knee replacement who took 220 mg of dabigatran etexilate daily had few major bleeding events regardless of their body mass index (BMI), renal function, or age, according to an international,...
Atlanta—Patients undergoing...
02/14/2013
First Report Managed Care