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AHA Scientific Statement

New American Heart Association Scientific Statement on Pulmonary Embolism Management & Outcomes

Pulmonary embolism (PE) is a life-threatening condition responsible for approximately 100,000 deaths per year in the U.S., and the incidence has increased over the past few decades. Black patients experience higher incidence, clinical severity and age-adjusted mortality rates from PE compared with other racial and ethnic groups.

A new scientific statement from the American Heart Association (AHA), Disparities in Current Pulmonary Embolism Management and Outcomes, summarizes differences in diagnosis, treatment strategies and long-term outcomes related to PE.

The statement:

  • Identifies differences in the diagnosis, presentation and management of PE associated with race, ethnicity, sex or socioeconomic status;
     
  • Highlights additional risk factors for PE such as oral contraceptives, pregnancy and hormone replacement therapy; and
     
  • Reviews approaches to create equitable PE care and address the knowledge gaps in the literature, including the need for representation in research and clinical trials.

Chaired by Edwin Takahashi, M.D., assistant professor of radiology in the division of interventional radiology at the Mayo Clinic in Rochester, Minnesota, the scientific statement published today, March 20, 2025, in the Association’s journal Circulation. Supporting materials for the statement, including Top Things to Know, are available here.

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