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The OCTIVUS trial was a head-to-head comparison of OCT- and IVUS-guided PCI with regards to clinical outcomes in patients with a broad range of coronary artery lesions.

Stent thrombosis was significantly reduced with OCT-guided PCI.

The ARREST trial investigated whether expedited transfer of OHCA patients to a cardiac arrest centre reduces mortality compared with delivery to the closest emergency department.

Intravascular imaging-guided percutaneous coronary intervention (PCI) is associated with a lower rate of target lesion failure compared with angiography-guided PCI.

STOPDAPT-3 investigated the efficacy and safety of aspirin-free prasugrel monotherapy compared with 1-month DAPT with aspirin and prasugrel in patients with ACS or HBR undergoing PCI with cobalt-chromium everolimus-eluting stents.

Principal investigator Professor Holger Thiele said: “The results of ECLS-SHOCK demonstrated no reduction in 30-day mortality with early ECLS therapy and an increase in complications."

The FIRE trial examined whether complete revascularization based on coronary physiology is superior to a culprit-only strategy in older patients with MI and multivessel disease.

The medical management of patients with severely reduced LVEF has improved dramatically. Novel drugs were introduced that lower the risk of sudden cardiac death.

The document covers the management of unstable angina and all types of acute myocardial infarction.

Infective endocarditis refers to an infection of the heart’s inner lining, most frequently the heart valves. It occurs when bacteria or fungi enter the bloodstream, for example through skin infections, dental procedures and surgery.